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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ADCY1
All Species:
22.73
Human Site:
S543
Identified Species:
55.56
UniProt:
Q08828
Number Species:
9
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q08828
NP_066939.1
1119
123440
S543
R
R
A
L
R
T
A
S
E
K
L
R
N
R
S
Chimpanzee
Pan troglodytes
XP_519081
1119
122966
S543
R
R
A
L
R
T
A
S
E
K
L
R
N
R
S
Rhesus Macaque
Macaca mulatta
XP_001086268
1119
123304
S543
R
R
A
L
R
T
A
S
E
K
L
R
N
R
S
Dog
Lupus familis
XP_849081
1161
127825
S527
R
R
A
L
R
T
A
S
E
K
L
R
N
R
S
Cat
Felis silvestris
Mouse
Mus musculus
O88444
1118
123354
S542
R
R
A
L
R
T
A
S
E
K
L
R
N
R
S
Rat
Rattus norvegicus
Q03343
1166
130488
E619
A
Q
D
A
L
N
P
E
D
E
V
D
E
F
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q9DGG6
1334
149273
V687
E
K
G
R
W
G
G
V
S
L
D
Q
S
A
L
Frog
Xenopus laevis
P98999
1305
145393
C625
T
L
K
S
C
P
S
C
G
E
T
A
A
R
D
Zebra Danio
Brachydanio rerio
NP_001161821
1114
124608
S536
R
R
A
L
R
T
A
S
E
K
L
R
N
R
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P32870
2248
248806
K638
S
Q
S
K
V
A
D
K
F
K
R
P
F
R
K
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
97.5
98.7
62
N.A.
92.5
39.6
N.A.
N.A.
27.3
28.8
71.4
N.A.
21.5
N.A.
N.A.
N.A.
Protein Similarity:
100
98.2
99
68.2
N.A.
95.2
55.8
N.A.
N.A.
43.4
44.7
81.4
N.A.
33.1
N.A.
N.A.
N.A.
P-Site Identity:
100
100
100
100
N.A.
100
0
N.A.
N.A.
0
6.6
93.3
N.A.
13.3
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
100
N.A.
100
26.6
N.A.
N.A.
20
20
100
N.A.
26.6
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
0
60
10
0
10
60
0
0
0
0
10
10
10
0
% A
% Cys:
0
0
0
0
10
0
0
10
0
0
0
0
0
0
0
% C
% Asp:
0
0
10
0
0
0
10
0
10
0
10
10
0
0
10
% D
% Glu:
10
0
0
0
0
0
0
10
60
20
0
0
10
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
10
0
0
0
10
10
0
% F
% Gly:
0
0
10
0
0
10
10
0
10
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
10
10
10
0
0
0
10
0
70
0
0
0
0
10
% K
% Leu:
0
10
0
60
10
0
0
0
0
10
60
0
0
0
20
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
10
0
0
0
0
0
0
60
0
0
% N
% Pro:
0
0
0
0
0
10
10
0
0
0
0
10
0
0
0
% P
% Gln:
0
20
0
0
0
0
0
0
0
0
0
10
0
0
0
% Q
% Arg:
60
60
0
10
60
0
0
0
0
0
10
60
0
80
0
% R
% Ser:
10
0
10
10
0
0
10
60
10
0
0
0
10
0
50
% S
% Thr:
10
0
0
0
0
60
0
0
0
0
10
0
0
0
10
% T
% Val:
0
0
0
0
10
0
0
10
0
0
10
0
0
0
0
% V
% Trp:
0
0
0
0
10
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _